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Активные Фармацевтические Вещества

Благодаря нашим установкам по качеству, современным производствам и аккредитации глобального управления, Гриндекс является одним из наиболее востребованных на мировом рынке поставщиков АФВ. АФВ производятся в соответствии с требованиями НПП, в соответствии с сертификацией, в том числе о соответствии производителя НПП.

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A-Z
Antazoline phosphate

  • INN

    Antazoline phosphate

  • Therapeutic use

    Antihistaminic

  • Quality application

    USP ASMF (Active Substance Master File)

  • CAS number

    154-68-7

  • Status

    Under Contractmanufactring

  • Usage

    For human use

  • Chemical name

    N–Benzyl-N–(4,5-dihydro-1H–imidazol-2-ylmethyl)aniline phosphate

  • Molecular formula

    C17H19N3 • H3PO4

  • Molecular weight

    363.35

  • Structure

Atipamezole hydrochloride

  • INN

    Atipamezole hydrochloride

  • Therapeutic use

    Antidote to a2-adrenoceptor induced sedation (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    104075-48-1

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride

  • Molecular formula

    C14H16N2 • HCl

  • Molecular weight

    248.76

  • Structure

Bortezomib

  • INN

    Bortezomib

  • Therapeutic use

    Proteasome inhibitor

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    179324-69-7

  • Status

    Under developemnt

  • Usage

    For human use

  • Chemical name

    [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid

  • Molecular formula

    C19H25BN4O4

  • Molecular weight

    384.24

  • Structure

Dasatinib

  • INN

    Dasatinib

  • Therapeutic use

    Tyrosine kinase inhibitor

  • Quality application

    Under developemnt

  • CAS number

    302962-49-8

  • Status

    Under developemnt

  • Usage

    For human use

  • Chemical name

    N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide

  • Molecular formula

    C22H26CIN7O2S

  • Molecular weight

    488.01

  • Structure

Desaminooxytocin

  • INN

    Desaminooxytocin

  • Therapeutic use

    Uterotonic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    113-78-0

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    1-(3-Mercaptopropanoic acid)oxytocin

  • Molecular formula

    C43H65N11O12S2

  • Molecular weight

    992.19

  • Structure

Detomidine hydrochloride

  • INN

    Detomidine hydrochloride

  • Therapeutic use

    Sedative (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    90038-01-0

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-[(2,3-Dimethylphenyl)methyl]-1H-imidazole hydrochloride

  • Molecular formula

    C12H14N2 • HCl

  • Molecular weight

    222.72

  • Structure

Dexmedetomidine hydrochloride

  • INN

    Dexmedetomidine hydrochloride

  • Therapeutic use

    Sedative, analgesic

  • Quality application

    USP and Ph.Eur. ASMF (Active Substance Master File) under development

  • CAS number

    145108-58-3

  • Status

    Commercially available

  • Usage

    For human and veterinary use

  • Chemical name

    4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

  • Molecular formula

    C13H16N2 • HCl

  • Molecular weight

    236.74

  • Structure

Droperidol

  • INN

    Droperidol

  • Therapeutic use

    Neuroleptic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability), Ph.Eur. ASMF (Active Substance Master File), USP ASMF (Active Substance Master File)

  • CAS number

    548-73-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-2-=1,3-dihydro-2H-benzimidazol-2-one

  • Molecular formula

    C22H22FN3O2

  • Molecular weight

    379.43

  • Structure

Imatinib mesilate

  • INN

    Imatinib mesilate

  • Therapeutic use

    Tyrosine kinase inhibitor, antineoplastic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    220127-57-1

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]= phenyl]benzamide methanesulfonate

  • Molecular formula

    C29H31N7O • CH4SO3

  • Molecular weight

    589.70

  • Structure

Medetomidine hydrochloride

  • INN

    Medetomidini hydrochloride

  • Therapeutic use

    Sedative, analgesic (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    86347-15-1

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride

  • Molecular formula

    C13H16N2 HCl

  • Molecular weight

    236.74

  • Structure

Oxytocin

  • INN

    Oxytocinum

  • Therapeutic use

    Uterotonic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File) USP ASMF (Active Substance Master File) USP VMF Complete Document

  • CAS number

    50-56-6

  • Status

    Commercially available

  • Usage

    For human and veterinary use

  • Chemical name

    L-Cysteinyl-L-Tyrosyl-L-Isoleucyl-L-Glutaminyl-=L-Asparaginyl-L-Cysteinyl-L-Prolyl-L-Leucylglycinamide cyclic (1->6) disulfide

  • Molecular formula

    C43H66N12O12S2

  • Molecular weight

    1007.20

  • Structure

Pemetrexed disodium

  • INN

    Pemetrexed disodium

  • Therapeutic use

    Antineoplastic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) under development

  • CAS number

    150399-23-8

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt

  • Molecular formula

    C20H19N5Na2O6

  • Molecular weight

    471.37

  • Structure

Pimobendan

  • INN

    Pimobendan, Pimobendanum (in Latin)

  • Therapeutic use

    Cardio Vascular (vet.)

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    74150-27-9

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    6-[2-(4-Methoxyphenyl)-3H-benzimidazol-5-yl]-5-methyl-4,5-dihydro-2H-pyridazin-3-one

  • Molecular formula

    C19H18N4O2

  • Molecular weight

    334.37

  • Structure

Rilmenidine dihydrogen phosphate

  • INN

    Rilmenidini dihydrogenphosphas

  • Therapeutic use

    Antihypertensive

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    85409-38-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine dihydrogen phosphate

  • Molecular formula

    C10H16N2O • H3PO4

  • Molecular weight

    278.24

  • Structure

Solifenacin succinate

  • INN

    Solifenacin succinate

  • Therapeutic use

    Antimuscarinic

  • Quality application

    Ph.Eur. ASMF (Active Substance Master File) under development

  • CAS number

    242478-38-2

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate

  • Molecular formula

    C23H26N2O2 • C4H6N2O4

  • Molecular weight

    480.55

  • Structure

Sunitinib

  • INN

    Sunitinib

  • Therapeutic use

    Receptor tyrosine kinase inhibitor

  • Quality application

    API is under development

  • CAS number

    341031-54-7

  • Status

    Under development

  • Usage

    For human use

  • Chemical name

    N-(2-diethylaminoethyl)-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

  • Molecular formula

    C19H25BN4O4

  • Molecular weight

    398.48

  • Structure

Tegafur (Ftorafur)

  • INN

    Tegafur

  • Therapeutic use

    Cytostatic

  • Quality application

    JP/Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    17902-23-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-(1H,3H)-pyrimidinedione

  • Molecular formula

    C8H9FN2O3

  • Molecular weight

    200.17

  • Structure

Tioguanine

  • INN

    Tioguanine

  • Therapeutic use

    Cytostatic

  • Quality application

    BP ASMF (Active Substance Master File)

  • CAS number

    154-42-7

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    2-Amino-1,7-dihydro-6H-purine-6-thione

  • Molecular formula

    C5H5N5S

  • Molecular weight

    167.19

  • Structure

Ursodeoxycholic acid

  • INN

    Ursodeoxycholic acid

  • Therapeutic use

    Anticholelithogenic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability), Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    128-13-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-(3,7-Dihydroxy-10,13-dimethyl- 2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H- cyclopental[a]phenanthren-17-yl)pentanoic acid

  • Molecular formula

    C24H40O4

  • Molecular weight

    392.58

  • Structure

Xylazine

  • INN

    Xylazinum

  • Therapeutic use

    Sedative, analgesic, muscle relaxant (vet.)

  • Quality application

    USP VMF Complete Document, USP ASMF (Active Substance Master File)

  • CAS number

    7361-61-7

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine

  • Molecular formula

    C12H16N2S

  • Molecular weight

    220.34

  • Structure

Xylazine hydrochloride

  • INN

    Xylazini hydrochloride

  • Therapeutic use

    Sedative, analgesic, muscle relaxant (vet.)

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File) USP ASMF (Active Substance Master File)

  • CAS number

    23076-35-9

  • Status

    Commercially available

  • Usage

    For veterinary use

  • Chemical name

    N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride

  • Molecular formula

    C12H16N2S • HCl

  • Molecular weight

    256.80

  • Structure

Zopiclone

  • INN

    Zopiclone

  • Therapeutic use

    Hypnotic

  • Quality application

    Ph.Eur. CEP (Certificate of Suitability) Ph.Eur. ASMF (Active Substance Master File)

  • CAS number

    43200-80-2

  • Status

    Commercially available

  • Usage

    For human use

  • Chemical name

    4-methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4b]-pyrazin-5-yl este

  • Molecular formula

    C17H17ClN6O3

  • Molecular weight

    388.81

  • Structure

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